Abstract
In the course of the study on FAD stability in aqueous solution, two kinds of mold and one kind of bacterium having FAD decomposing ability were isolated from the FAD solution in which decrease of the co-enzymatic activity of FAD during preservation was observed. The mechanism of the FAD decomposition by these microorganisms has not yet been clarified. It was, however, suggested that the adenosine moiety of FAD was preferably utilized by these organisms. Furthermore, it was found that these organisms produced phosphatase which hydrolyzed FAD to FMN or riboflavin. FAD decomposition in aqueous solution by other kinds of mold was also observed, while lactic bacteria tested exerted no decomposing effect on the substance.
