抄録
Riboflavin tetrabutyrate, riboflavin tetracaprate, and riboflavin tetrapalmitate were synthesized by our method and riboflavin tetraacetate was synthesized by the esterification of riboflavin with acetic acid anhydride. To test the possibility of the hydrolysis of these esters in living body, the authors first examined the hydrolysis of these esters by pancreatic lipase. The results showed that the above four esters tested were hydrolyzed to riboflavin and corresponding fatty acids. Among them, riboflavin tetrabutyrate was most easily hydrolyzed and followed by tetracaprate, tetraacetate and tetrapalmitate.
