Abstract
The histopathological studies on the lesion of nervous tissues in the experimentally produced vitamin E deficient rats were performed and the results obtained were as follows. The degenerative changes were found in several nuclei of the brain and spinal cord, most marked in the pyramidal tract. Similar changes were observed in the peripheral neurons in the stomach, intestine, uterus, etc. The degeneration of nerve fibers and end-plates, which preceded the changes of skeletal muscle, were seen.