ABSORPTION OF S-BENZOYLTHIAMINE MONOPHOSPHATE AND ITS EFFECT ON AMINO ACID ABSORPTION

Abstract

Comparative studies on the intestinal absorption and effect on amino acid absorption of S-benzoylthiamine monophosphate, a derivative of thiamine, and thiamine hydrochloride were carried out. Absorption from the intestine of the former was greater. No effect on amino acid absorption was observed with either agent in in vitro experiments but in vivo, both had a suppressive effect. This suppressive effect was prevented by pyridoxine in the case of thiamine hydrochloride.