Abstract
Using young white rats submitted to deficiency during suckling and weaning period, the author studied histochemical distribution of thiamine in the organs before and after weaning. Even in advanced stages of thiamine deficiency, nervous cells in cerebrum and epithelium of digestive tracts, especially of intestine maintained a relatively high content of thiamine. Decrease in thiamine was more marked in renal tubuli than in glomeruli. The thiamine content in white pulp of spleen, especially in secondary nodules markedly reduced, reacting sensitively to thiamine deficiency. Stratum germinativum in epidermis showed rapid decrease in thiamine content at early stage of thiamine deficiency.
