Abstract
Thiamine dicetylsulfate or thiamine hydrochloride was administered orally to chicks of 400〜500g and the sites of absorption in digestive tracts were determined by means of the chromic oxide index methed. At the middle of small intestine, the absorption coefficient of thiamine hydrochloride was found to be 75 per cent, while that of thiamine dicetylsulfate was 55 per cent, and at the lower end of small intestine, the coefficients were 90 and 85 per cent, respectively. Thiamine contents of free and ester forms in chick organs and pyruvic acid content in blood were determined 1-5 hours after an administration. In blood and liver, increases in the free thiamine contents were observed at first, then the contents of esterified thiamine increased while the free thiamine contents decreased. These changes in thiamine contents occured faster when thiamine hydchloride was given than the case that thiamine dicetylsulfate was given. No change was observed in the muscle thiamine content. When thiamine hydrochloride was administered to chick, the pyruvate content in blood decreased significantly 1 hour after an administration, but when thiamine dicetylsulfate was given, the decrease in blood pyruvate content was observed after 5 hours.
