抄録
Investigations were made on the absorption and excretion of S-carbalkoxythiamine (CAT). When CAT was administered on healthy man per os, the thiamine level of blood and thiamine elimination in urine were higher than in case of thiamine hydrochloride administration. This fact shows CAT is easily absorbable than thiamine hydrochloride. In the case of injection into the gut of dog or rat, CAT was found in itself in portal vein, but not in liver. Thus it is supposed that CAT is absorbed from gut in itself and a part of it is hydrolysed to thiamine in portal vein and the remainder in liver.