抄録
Treatment of anhydrous formamide and pyridine solution of a mixture of thiamine-5-phosphate and adenosine-5-phosphate with dicyclohexylcarbodiimide at room temperature for one day gave linear thiamine adenosine diphosphate (I) as a main products. By a similar procedure the thiamine inosine diphosphate (II) was synthesized from thiamine-phosphate with inosine-5-phosphate. II was obtained also from I by deamination with nitrous acid. Purification was achieved in each by the rechromaography on anion- and week cathion exchange resins.
