抄録
This paper deals with the experiments bearing on the structure of thiaminosuccinic acid, a product formed during conversion of oxythiamine to thiamine by E.coli thiamine-less mutant. The compound isolated from the incubation product of the bacteria with oxythiamine and aspartic acid was identical with synthetic 3-[2-methyl-4-(1,2-dicarboxyethylamino)-5-pyrimidylmethyl]-4-methyl-5-(2-hydroxyethyl) thiazole in UV and IR spectra, paper chromatographic and paper ionophoretic behaviors, microbiological activities, etc., Chemical synthesis of the new compound was described.
