ピリミジン誘導体の研究 : (XXXIV)O, S-Dicholanoylthiamine誘導体の合成
1965 年 31 巻 3 号 p. 210-213
詳細
1965 年 31 巻 3 号 p. 210-213
From the biological interest, five O, S-dicholanoylthiamine derivatives (I-V) were synthesised by the reaction of corresponding cholanoyl chloride with thiamine in alkaline medium. The compounds obtained here are insoluble in water and soluble in chloroform or ethyl acetate. These compounds are negative to thiochrome reaction, but become positive after treatment with alkali. The regeneration of thiamine and cholanic acid was shown. Biological test are now undertaken.
