Abstract
Some biological properties of thiamine monophosphate disulfide (TMPDS) was studied. TMPDS exerts approximately equal growth promoting effects for thiamine requiring organisms, L. fermenti 36 and rat. Partially purified thiaminases of bacilli could scarcely decomposed this compound. TMPDS is readily absorbed in man, rat, rabbit and guinea pig, by oral or parenteral administration and consequently higher content of thiamine and co-carboxylase were found in blood or organs of the animal in comparison to thiamine hydrochloride.
