Abstract
Pharmacological effects of thiamine monophosphate disulfide (TMPDS) on acute toxicity of mice, the blood pressure of cats, hearts of dogs, guinea pigs and toads, and the movement of small intestines of guinea pigs and rabbits were studied in comparison with those of thiamine hydrochloride. The experimental results showed that the dynamic pharmacological effects of TMPDS on them were less remarkable than those of thiamine hydrochloride.