抄録
Some biological properties of a new thiamine derivative, O-acetoglycoloyl-S-furoylthiamine (AFT) was investigated. In thiamine-requiring organisms, AFT exerted almost equal growth-promoting effects to that of thiamine hydrochloride. In thiamine deficient rat, longer duration of this effects were observed at higher dose of AFT. Purified thiaminases of bacilli could not decompose this compound. As compared with thiamine hydrochloride, AFT produced higher thiamine and cocarboxylase levels in blood by parenteral administrations. This high levels of thiamine and cocarboxylase were maintained for many hours.
