Abstract
Twenty rural children were administered riboflavin or vitamin B_6 together with other vitamins in an attempt to determine whether the urinary excretion of keto- and 17-OH-corticoid would reflect the administration of these vitamins. In addition, tryptophan load test was conducted. The result showed that the urinary pattern of corticoids was improved significantly and xanthurenic acid excretion was decreased remarkably after supplementation of vitamin B_6 as well as riboflavin. From the data presented, it seems that some of the children were deficient in riboflavin and vitamin B_6 and this may cause stresses and disorder of tryptophan metabolism in them.
