抄録
Palmitoyl- and dipalmitoyl-ascorbic acids in bile salt solution have been found to be hydrolyzed readily by the homogenate of pancreas, liver and intestine but the ratio of hydrolysis of these esters varies with changes of their micellar compositions in the reactive system. There have also been found considerable differences about both of the extent and the rate on hydrolysis of these esters on the same ratio of their micellar composition, or even on the simulated human intestinal content with respect to Na^<+>(0.15M), bile salt (0.04M), pH (6.3) and temperature (37℃). From these results it may be partially explained that there is a great difference in the body retention or availability between palmitoyl ascorbic acid and dipalmitoyl ascorbic acid, as shown in our previous report.