抄録
The influence of vitamin E on the osmotic fragility of preserved erythrocyte was investigated. The blood samples were obtained from 10 normal persons in citrate・phosphate・glucose solution. Alpha-tocopheryl-acetate was added with the concentration of 10,20 or 50 mg%. The osmotic fragility was measured by Dacie's method, once or twice a week for 3 to 4 weeks. The osmotic fragility was evidently increased in control and tocopherol groups, but it was less marked in the latter. The protective potency of the increase of osmotic fragility was the order of 50mg>20mg>10mg of tocopherol. These results show that vitamin E lessens the increase of osmotic fragility of erythrocyte in preserved blood.
