Abstract
Pantothenic acid, CoA and their intermediates in rat liver were isolated by using DEAE-cellulose column chromatography and identified by means of paper chromatography. In rat liver CoA exsisted in the largest amounts and 4'-phosphopantetheine in second order. Pantothenic acid was recognized in very small amounts from this experiment. By the addition of CoA to rat liver sample, it was confirmed that very small amounts of 4'-phosphopantetheine was released by decomposition of CoA during the preparation of rat liver sample, but all 4'-phosphopantetheine present in preparation did not mean to derive from decomposition of CoA alone. In our future study the relation between 4'-phosphopantetheine and acyl carrier protein would be investigated.
