抄録
^<35>S-Thiamine or ^<35>S-0-nicotinylthiamine disulfide was administered orally to mice with liver injury due to CCl_4. There was decrease in liver uptake in respect to control. After ^<35>S-O-nicotinylthiamine disulfide was treated liver uptake decreased first, but as compared to control, markedly increased in 24 hours. When O-nicotinylthiamine disulfide was given 500mg to patients with liver damage, there was, as compared to patients with other disease, greater urinary excretion of vitamin B_1 in 24 hours.
