Abstract
The influence of vitamin E on platelet count of rats associated with decompression was studied. In the first study, when rats stayed at 6 absolute atmosphere (ATA) for 2 hours and were decompressed in 15 minutes, platelet count fell from 56.13±4.14×10^4/mm^3 to 39.06±12.98×10^3/mm^3 after decompression. In the second study, rats were divided into 3 groups: group A rats were fed vitamin E-deficient diets (d-α-tocopherol 5mg/kg), group B rats were fed the control diets (dl-α-tocopheryl acetate 20mg/kg), and group C rats were the vitamin E diets (dl-α-tocopheryl nicotinate 234mg/kg). These groups were fed for 3 months. Platelet count fell from 64.84±3.70×10^4/mm^3 to 56.66±5.03×10^4/mm^3 after the decompression in group A. Platelet count fell from 56.28±3.12×10^4/mm^3 to 45.62±13.84×10^4/mm^3 in group B. But there was no significant changes of platelet in group C. In the third study, survival rate after decompression was studied. The highest survival rate was observed in group C (50.0%) and the lowest survival rate was in group A (16.7%). These resutls suggest that platelets changes after decompression are inhibited by vitamin E.
