Abstract
The absorption of topically applied thiamin and thiamin tetrahydrofurfuryl disulfide (TTFD) by the rat has been studied. Thiamin concentrations were high in blood and liver of 5% thiamin or 5% TTFD administered rat. After topical application of ointment for 2hrs, thiamin concentrations were significantly high in liver, spleen, kidney and blood of thiamin (5%) administrated rats, and in brain, liver, spleen, kidney, muscle and blood of the administered rats compared with those of control rats.
