抄録
The nutritional effects of calcium ascorbate as a calcium source on plasma calcium metabolism and bone growth were investigated in vitamin D-deficient rats. Rats were fed ad libitum diets containing calcium ascotbate or calcium carbonate as a calcium source for 4 weeks with low dose of vitamin D3. During feeding, body weight, food consumption and calcium intake were recorded. After feeding, the concentrations of calcium, phosphorus, parathyroid hormone, alkaline phosphatase activity, 25-hydroxyvitamin D_3 and 1α,25-dihydroxyvitamin D_3 in plasma were determined. Mineral density, mechanical strength and ash weight in femur were measured. Calcium metabolism and bone growth in the calcium ascorbate group improved more significantly than the calcium carbonate group. These results suggest that calcium ascotbate could be an effective calcium source.