Abstract
The administration of pituitrin did not cause any significant change in the thiamine content of several tissues of normal rats. The ratio of bound thiamine to free one was not affected by this hormone. But in alloxan diabetic rats the thiamine content in liver and kidney increased after pituitrin and its phosphory1ation rate was enhanced. When pituitrin was administered together with thiamine to diabetic rats, the increase of thiamine content was much more considerable than when thiamine alone was used and its phosphorylation was also promoted. In normal rats these effects of pituitrin were only slight.
