Crystal Structure of 1-(2,3,4-Trimethoxybenzyl)piperazine monohydrochloride

抄録

Trimetazidine is an anti-ischemic agent. The structure of trimetazidine hydrochloride, C₁₄H₂₂N₂O₃·HCl, was determined by X-ray crystallography. The compound crystallizes in a monoclinic system, space group P2₁/c and cell parameters: a = 21.548(1)Å, b = 7.6273(3)Å, c = 9.5982(5)Å, β = 100.651(2)°, Z = 4, V = 1550.32(12)ų. The crystal structure was solved by direct methods and refined by full-matrix least-squares on F² to final values of R1 = 0.055 and wR2 = 0.118.