YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Symposium Reviews
Effect of Nanocarbon Sizes on the Cellular Uptake
Minfang ZhangMasako Yudasaka
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JOURNAL FREE ACCESS

2013 Volume 133 Issue 2 Pages 151-156

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Abstract
  Single-walled carbon nanohorn (CNH) is a type of nanocarbon that is a single-graphene nanometer-sized pseudo tubule with a diameter of 2-5 nm and a length of 40-50 nm. About 2000 CNHs assemble to form a spherical aggregate with a diameter of about 100 nm. CNHs have low toxicity and their potential medical applications have therefore attracted much research attention. In this report, we show that the cellular uptake of CNHs can be controlled by chemical functionalization of the CNH surface and that the controllability can be enhanced by downsizing the CNH aggregates.
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© 2013 by the PHARMACEUTICAL SOCIETY OF JAPAN
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