YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
総説
服薬アドヒアランス向上を目指した製剤開発
並木 徳之
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ジャーナル フリー

2021 年 141 巻 10 号 p. 1173-1184

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Medication adherence is an important factor in the success or failure of drug treatment. No matter how good a drug is, if a patient cannot or does not want to take it, the therapeutic effect of the drug will not be sufficient and as expected. Therefore, we have been developing formulations with “clinical functionality”, namely, formulation characteristics that enhance the likelihood of obtaining the expected therapeutic effect. We researched formulations that are easy to take and deliver expected results; these formulations include gummy drugs as confectionery-like formulations and orally disintegrating (OD) tablets that can be easily swallowed. In particular, OD tablets have been jointly developed with pharmaceutical companies and have been commercialized. Clinical trials with gummy drugs and OD tablets have been conducted to verify the impact of these formulations with clinical functionality on improving medication adherence.

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