Studies on the N-Aminoacylaminosugar. I. Synthesis of N-Lysyl-D-glucosamine and Its Related Compounds

Abstract

N-L-Lysyl-D-glucosamine and its derivatives were synthesized as model compounds of N-aminoacylaminosugars which are commonly found in the structure of streptothricin and related antibiotics. L-Lysine was condensed with the amino group of D-glucosamine and the aminoacyl chain was elongated stepwise with the same amino acids.