1981 Volume 101 Issue 1 Pages 78-81
Rice bran lectin (RBL) agglutinated human erythrocytes regardless of their ABO and MN blood-group systems. The receptor activity of erythrocytes against RBL was completely abolished by treatment with pronase for two hours and partially abolished by treatment with trypsin or α-chymotrypsin for three hours. Sialoglycopeptides released from human erythrocytes by treatment with protease such as pronase, trypsin or α-chymotrypsin inhibited the hemagglutination by RBL. Removal of sialic acid residues of sialoglycopeptides diminished their inhibitory activities. Among sugars tested, only N-acetyl-D-glucosamine showed hemagglutinating inhibition.
