抄録
Membrane potentials and membrane permeability coefficients of bovine eye-lens capsule and cellulose membrane were measured for L-phenylephrine HCl (mydriatic), its related compounds [DL-phenylpropanolamine HCl, and phenethylamine HCl] as well as pilocarpine HCl (myotic) and sodium chloride. It has been found that there is fairly strong interaction between phenylephrine cation and capsule, and also that pilocarpine HCl makes capsule more porous, so that its permeability coefficient across the capsule becomes large compared to other substances.
