生理活性を有する天然ステロール : 特に側鎖の立体構造とその生理的意義について
1981 年 101 巻 9 号 p. 753-773
詳細
1981 年 101 巻 9 号 p. 753-773
In the past decade, the nutrization, metabolism and function of natural sterols in animals have become an intensely investigated area of physiology and biochemistry, and direct studies toward the physiological, biochemical and chemical aspects of this problem have greatly expanded our knowledge of this area. In this review, sterol metabolism in insects, ecdysone biosynthesis, synthesis and biological activities of vitamin D3 metabolites (23, 25-dihydroxyvitamin D3 and calcidiol lactone), stereoselective introduction of hydroxy group in the sterol side chain, synthesis of brassinolide, which have been investigated in the author's laboratory, are described, and the conformation of sterol side chain is also discussed.
