Catalytic Hydrogenation of Acridone Alkaloids in the Presence of Platinum Catalyst

Abstract

Catalytic hydrogenation of acridone alkaloids over platinum catalyst under acidic conditions was examined. The A-and/or C-ring in acridones having only O-substituents were hydrogenated together with hydrogenolytic elimination of O-substituents. On the other hand, the C-ring in pyranoacridones was found to resist the hydrogenation even in acidic solution.