YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
発癌性および非発癌性メチル置換ベンツ[c]アクリジン類の簡易な精製法
本橋 登鎌田 国広
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1983 年 103 巻 7 号 p. 795-799

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The trace amount of by-products co-existing with a large amount of thin layer chromatography (TLC) untreated benz [c] acridines (BAc) were defined by using TLC, high performance liquid chromatography (HPLC), gas chromatography (GC) and GC-mass spectrometry (GC-MS). Twelve BAc were separated by TLC on a silica gel 60 GF254. TLC-treated BAc showed one spot on TLC and were determined by HSLC, GC and GC-MS. This method using TLC for purifying BAc suggested to be very useful and simple.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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