Studies on the Constituents of Cucurbitaceae Plants. XII. On the Saponin Constituents of Gynostemma pentaphyllum MAKINO (8)

Abstract

Five dammarane-oligoglycosides named gypenosides XLVII (1), XLVII (2), XLIX (3), L (4) and LI (5) were isolated from the aerial parts of Gynostemma pentaphyllum MAKINO collected in Tokushima pref. On the basis of chemical and physicochemical evidence, they were characterized as follows : 1, 2α, 3β, 12β, 20 (S), 26-pentahydroxydammar-24-ene-3-O-β-sophoroside-20-O-β-rutinoside : 2, 19-oxo-3β, 20 (S), 21-trihydroxydammar-24-ene-3-O-{[α-rhamnopyranosyl (1→2)] [β-glucopyranosyl (1→3)]-α-L-arabinopyranoside}-21-O-β-glucopyranoside : 3, 19-oxo-3β, 20 (S), 21-trihydroxydammar-24-ene-3-O {[α-rhamnopyranosyl (1→2)] [β-glucopyranosyl (1→3)]-α-L-arabinopyranoside}-21-O-β-glucopyranoside : 4, 2α, 3β, 12β, 20 (S)-tetrahydroxydammar-24-ene-3-O-β-sophoroside : 5, 2α, 3β, 12β, 20 (R)-tetrahydroxydammar-24-ene-3-O-β-sophoroside.