二官能性炭素の反応およびその合成化学への利用

抄録

As are known by various sorts of the representative methylene type the bifunctional carbons, which signify the carbons linking two heterofunctional groups, have proved to furnish characteristic reactivities. That is to say, they can undergo easy substitution of their one-side group and receive insertion of unsatureted spieces into their one-side bond. The aim of author's investigation in this field was to develop basic reactions as well as new reagents which are useful for practicing organic chemists. This article is to review the work in this laboratory, which is constituted of numerous new reactions involving reduction, substitution, carbon-carbon bond formation, rearrangement, insertion, 1, 3-dipolar cycloaddition and so on, with development of new reagents such as formic acid-triethylamine azeotrope as a reducing agent, diazoalkane-generating agent and aromatic diazotategenerating agent. Application of the reactions to the syntheses of some physiologically active compounds is also briefly summarized.