YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Nitrite Ion, Its Stability in an Aqueous Solution and Disappearance from Rabbit Blood
HIROSHI NODAMASAO MINEMOTOSEIJI ETOATSUKO NODAKENJI MATSUYAMA
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1984 Volume 104 Issue 4 Pages 409-412

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Abstract
Heating and irradiation with room-fluorescent light as well as sunlight had little effect on the stability of a sterilized aqueous solution of sodium nitrite. Nitrite ion in an acidic medium became expectedly unstable with a considerable reduction of the half-life. After the intravenous injection of sodium nitrite solution to rabbits, the blood concentrations of nitrite ion decreased rapidly according to a first-order manner. The hydralazine-high performance liquid chromatography method employed here was proved to be useful for the determination of nitrite ion in biological and environmental samples.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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