Abstract
Heating and irradiation with room-fluorescent light as well as sunlight had little effect on the stability of a sterilized aqueous solution of sodium nitrite. Nitrite ion in an acidic medium became expectedly unstable with a considerable reduction of the half-life. After the intravenous injection of sodium nitrite solution to rabbits, the blood concentrations of nitrite ion decreased rapidly according to a first-order manner. The hydralazine-high performance liquid chromatography method employed here was proved to be useful for the determination of nitrite ion in biological and environmental samples.