YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
セトステアリルアルコールで安定化した水中油型エマルションの内部構造
福島 正二吉田 広一山口 道広
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1984 年 104 巻 9 号 p. 986-989

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The lamellar liquid crystalline phase (D2 phase) and a particle appearing in a region of a surfactant-cetostearyl alcohol-water ternary system, and the particle of the emulsion which was made by substituting part of the cetostearyl alcohol for a liquid paraffin were observed using a cryo scanning microscope. The D2 phase gave an image of overlapped lamellae. The particle of ternary system consisted of spherically overlapped lamellae. The oil droplet in the emulsion was surrounded by the spherical lamellae, as if it were protected by the spherical lamellae. Thus the internal structure of the emulsion stabilized with cetostearyl alcohol can be described as follows. The particles consist of oil droplets and spherical lamellae which surround them. The outer phase is a dispersion of the D2 phase platelets in an aqueous phase to form a gel. The layer of the spherical lamellae becomes thin with decreasing cetostearyl alcohol content.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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