Sodium Borohydride Reduction of 1, 2, 3-Triazine Derivatives

Abstract

The reduction of substituted monocyclic 1, 2, 3-triazines with sodium borohydride in methanol afforded their 2, 5-dihydro derivatives. The reduction of their 2-methyl quaternary salts also gave the 2, 5-dihydro compounds. The reduction of their 1-oxides and 2-oxides yielded their deoxygenated products and 1, 4, 5, 6-tetrahydro compounds, respectively. The same reaction of 1-methyl-2-oxo-triazinium salts afforded their 1, 6-dihydro derivatives whose structures were elucidated by an X-ray crystallographic study.