YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
N-アルキルエチレンジアミンの口腔内細菌等に対する抗菌性について
上田 道広村田 慶史
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1989 年 109 巻 3 号 p. 184-187

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Six N-alkylethylenediamines were synthesized and antimicrobial activity of each compound against oral microorganisms such as Streptococcus mutans, Actinomyces viscosus and Actinomyces naeslundii, and some others were determined in vitro. Dodecyl or tetradecyl derivative possessed maximum bacteriostatic activity among the test compounds. On the other hand, killing time of S. mutans in aqueous solution decreased with increasing alkyl-chain length.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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