YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Protective Effects of the Stem of Berchemia racemosa SIEB. et ZUCC. on Experimental Liver Injuries
Noriko SATO, Setsuko OHTA, Nobuko SAKURAI, Asahi KAMOGAWA, Takao INOUE, Masato SHINODA
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Keywords: liver injury, Berchemia racemosa, carbon tetrachloride, α-naphthylisothiocyanate, cholestasis
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1995 Volume 115 Issue 4 Pages 295-306

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Abstract
The methanol extract and water extract from the stem of Berchemia racemosa (Rhamnaceae) showed protective effects on liver injuries induced by carbon tetrachloride (CCl4) and α-naphthylisothiocyanate (ANIT) in rats. The acetone extract of B. racemosa protected the liver injury induced by CCl4. One of the protective substances was identified as carpusin. Some fractions showed significant protective effects against the liver injury and cholestasis induced by ANIT.
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