YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Isomers of Ephedrine Allied Compounds. IV
Seizo KanaoKiyoshi Shinozuka
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1948 Volume 68 Issue 3-4 Pages 83-87

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Abstract
Treatment of N-benzoyl derivative of n-dianisylhydroxyethyl amine with HCl results in benzoyl transition to benzoate and, at the same time, dehydration occurs to give β-p-nitrobenzoylamino di-p-methoxystilbene as a by-product. Deamination of normal base gives n-hydro-anisoine. Dipiperonylhydroxyethylamine, obtained by treatment of tyrosine and glycine by piperonal under the presence of alcoholic potash solution and subsequent hydrolysis, seems to be iso-compound from the results of its de-amination and benzoyl transition. Iso-hydroxypiperoine, obtained by de-amination coincides with the substance obtained by Fittig-Reusen.
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