Abstract
Antiseptic power of chloronaphthols against soy sauce were tested and it was found that 4-chloro-1-hydroxynaphthalene and 1-chloro-2-hydroxynaphthalene acetate possessed strong antiseptic power which were far stronger than that of p-hydroxybenzoic acid esters. Growth inhibitory action of chloronaphthols against various microorganisms were tested and it was found that substitution by chlorine in naphthol increased such inhibitory action but the number of substituent was limited to one atom which imparted maximum action and the increase of chlorine atoms decreased germicidal strength. Although substitution with chlorine atom increased germicidal action, polysubstituent of chlorine and keto-compounds in which OH has been oxidized, are assumed to possess decreased germicidal action due probably to changes in physical properties. It has been found that the germicidal and anthelmintic properties of a compound went more or less in parallel, so that, if a compound having germicdal powers but having weak toxicity against higher animals could be found, it might be possible to find an excellent anthelmintics among them.
