YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ヂアルキルヂチオカルバミン酸亞鉛の製造について
高木 誠司田中 善正
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1949 年 69 巻 6-10 号 p. 298-299

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Three compounds, zinc dithiocarbamate (I), zinc dimethyl-dithiocarbamate (II) and zinc diethyl-dithiocarbamate (III), were prepared and their therapeutic effect against dermatic mycosis was tested in various drug forms. (III) was the most effective, followed by (II), (I) being the weakest. The most effective preparation was an ointment made of (III), talc powder, diethyl phthalate and vegetable oil, which gave relief to most of the patients tested by the application for 7-10 days. (III) was synthesized from NaOH, CS2 and diethylamine, reacted in an aqueous solution and Zn-sulfate solution added to the solution of diethyl-dithio-carbamate formed. (III) was obtained in a good yield.
Treadwell, Hall: “Analytical Chemistry” Nth English Edition, Vol. II, p. 671.

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