蝎毒の本態に関する研究 (第2報)
免疫学的考察
1950 年 70 巻 11 号 p. 629-632
詳細
1950 年 70 巻 11 号 p. 629-632
In order to prepare rabbit serum immune to buthotoxin, crude buthotoxin sulfate was injected subcutaneously into rabbits, later intravenously, in small portions. The completion of immunization on the 19th day (total dose of the venom used, 11320γ) was tested with mice and the immunization was recognized to be 1.33 times of m.l.d. of mice.
It was confirmed that the sera of cats and of nonpoisonous snake (Elaphe climacophora Boie) can detoxicate and neutralize buthotoxin to a slight degree.
The crystalline picrate of a component reported in the preceeding paper as being chemically unknown was identified as hydroxylamine picrate.
