YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Chemotherapeutics. XI
Syntheses of Sulfaminopyrimidines. (6)
Taizo MatsukawaBuhachiro OhtaKenzo Sirakawa
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1950 Volume 70 Issue 5 Pages 283-286

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Abstract
1) 2- and 6-Sulfanilamino-pyrimidines were synthesized by the condensation of sulfanilamide with 2- or 6-chloropyrimidines under the presence of alkali carbonate.
2) 6-Sulfanilaminopyrimidines were synthesized by the condensation of N4-acetylsulfanilamide and 6-chloropyrimidines under the presence of alkali carbonate.
3) Condensation of sulfanilamide with 2-chloro-4-methylpyrimidine under the presence of calcium carbonate gives N4-{4-methylpyrimidyl-(2)}-sulfanilamide.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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