YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ルチン類似化合体の薬理学的並びに化学的研究 (第6報)
3´, 4´-Dihydroxyflavonolの体内変化, 排泄及び毒性について
小沢 光
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1951 年 71 巻 11 号 p. 1191-1194

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It was found that the excretion of 3′, 4′-dihydroxyflavonol in urine and feces was very slight, being less than one-tenth of the amount administered. By paper partition chromatography, it was found that the urine contained three substances of different Rf values that must have been formed by physiological process. 3′, 4′-Dihydroxyflavonol was found to have no acute toxicity in mice, showing no histologic change in various organs after daily administration of the compound for 60 days.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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