1951 年 71 巻 3 号 p. 178-181
In order to synthesize γ-acetyllactic ester, the raw material to obtain dihydroresorcinol by cyclization, it was found that there are two effective methods, as follows.
1) By the condensation of methylene acetoacetic ester and malonic ester to γ-acetyl-α, γ-carbethoxylactic ester in a good yield, which is saponified by hydrochloric acid to γ-acetyl-lactic acid, follwed by esterification.
2) γ-Acetyl-γ-carbethoxybutyronitrile, obtained by the condensation of acetoacetic ester and acrylonitrile, is saponified by alcoholic sulfuric acid to γ-acetyllactic ester.