Studies on Vitamin B₁ and Related Compounds. XXXVIII

Isolation of Allithiamine

Abstract

Allithiamine, a compound formed by the reaction of vitamin B₁ and the component of garlic (Allium sativum L. var. japonicum Kitamura), was isolated in crystals of m.p. 132-133° (decomp.) as recrystallized from benzene, or of m.p. 141-142° (decomp.) as recrystallized from water. Molecular weight determination by the Barger method and analytical values suggest the empirical formula of C₁₅H₂₂O₂N₄S₂. It was assumed from absorption spectra and other properties that it possessed a structure similar to “Aneurindisulfid.”