YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Aconite Alkaloids. II
On the Alkaloids of Aconitum tasiromontanum Nakai
Eiji OchiaiToshihiko OkamotoTsutomu SugasawaHidewo Tani
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1952 Volume 72 Issue 12 Pages 1605-1607

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Abstract
Aconitum tasiromontanum Nakai roots (Tashiroyamabushi) were collected in the forests around Nasu-Sandogoya, in central Japan, and their alkaloid content was examined. Crude base was obtained in approximately 0.1% yield as against fresh root. Of the crude base, 64% precipitate out from the hydrochloric acid solution upon the addition of ammonia water, and 9.8% are obtained by extraction of its mother liquor with chloroform. Purification of the former by chromatography yielded hypaconitine, mesaconitine, aconitine, and ignavine, as crystalline bases. The characteristics of this plant are that its alkaloid contains a very large amount of mesaconitine, a small amount of hypaconitine and aconitine, and that it contains, although in a small amount, the newly found ignavine.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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