Of the 74 kinds of compounds tested, following 10 were able to inhibit the growth of tubercle bacilli (human type) in vitro in concentrations above 160, 000 dilutions, whereas the same degree of growth inhibitory action was shown in 160, 000-320, 000 dilutions of sodium p-aminosalicylate used as a control: Phenanthrenequinone, thymoquinone, thymoquinone mono (aminoguanyl) hydrazone nitrate, p-benzoquinone, p-benzoquinone mono-(aminoguanyl) hydrazone, 1, 4-naphthoquinone, 1, 4-naphthoquinone mono (aminoguanyl) hydrazone nitrate, 2-methyl-1, 4-naphthoquinone, 2-methylanthraquinone, and p-sulfonamidobenzaldehyde thiosemicarbazone. Phenyl p-aminosalicylate seemed to be hopeful as it was able to inhibit the growth of tubercle bacilli in 1, 600, 000 to 6, 400, 000 dilutions.
Of the lichen components tested, none showed remarkable tuberculostatic actionn except that some inhibftion of the growth of tubercle bacilli was witnessed with 80, 000 dilution of methyl evernate, and in 40, 000 dilutions of methyl and propyl esters of atranorin and lecanoric acid, and isobutyl and amyl esters of evernic acid.
