γ-ブチロラクトン誘導体の研究 (第2報)

β,γ-及びα,β,γ-置換γ-ブチロラクトン類の合成

抄録

Sixteen kinds of β, γ- or α, β, γ-substitution products of γ-butyrolactone, including 13 new compounds, were prepared by heating under stirring with 85% sulfuric acid the ethyl esters of β-hydroxy acids obtained by the Reformatzsky reaction of various ketones and ethyl esters of α-bromo fatty acids. The compounds synthesized were all oily substances possessing individually characteristic aroma, and their hydrazinolactones were generally difficult to crystallize with the exception of the α, γ-substituted products and α, β, γ-substituted products possessing cyclohexyl ring which were comparatively easy to crystallize.