チアゾール誘導体の研究 (第4報)

2-Phenylimino-4-thiazolidoneの閉環反応に就いて

抄録

Condensation of α, β-dichlorovinyl alkyl ethers, where the alkyl is ethyl, butyl, or hexyl, and phenylthiourea results in the formation of 2-phenylimino-4-thiazolidone in all cases. As a result of detailed examination of this cyclization, it was assumed from experimental results that S-[β-chloro-β-alkoxyvinyl-(α)]-phenylisothiourea is formed as an intermediate which underwent liberation of alkyl chloride when heated with water to a ketene compound and changed finally to 2-phenylimino-4-thiazolidone.